GEO series
Longitudinal ovarian cancer (BOB)
GSE289067
Homo sapiens
Expression profiling by high throughput sequencing
183 samples
2025/02/08
GPL24676
Summary
High-grade serous ovarian cancer presents significant challenges due to its poor prognosis and high heterogeneity, both of which complicate treatment responses. This project aims to understand intra-patient tumor evolution by investigating different sampling sites (primary and metastatic) at the time of diagnosis and during disease recurrence. A total of 183 biopsies from 50 patients were collected for this purpose, and bulk mRNA sequencing was performed. The majority of samples originated from following tissue types: omentum, ovary, and ascites.
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Paper (PMID 41397972) ↗
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