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EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer [MRTX1133]

GSE289498 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/03/04 Platform GPL19057
Summary
We used RNA-Seq to profile APCmin, KRASG12D, TP53 murine organoids in the presence and absence of EGFR in combination with control or MRTX1133 (100 nM) treatment.
Published in
EGFR controls transcriptional and metabolic rewiring in KRAS(G12D) colorectal cancer
Krauß D, Moreno-Viedma V, Adachi-Fernandez E et al. · EMBO molecular medicine 2025 · PMID 40329096 · doi:10.1038/s44321-025-00240-4
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Also filed as BioProject PRJNA1223314 and SRA study SRP563664. Searching any of these in the dataset finder brings you back here.

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