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OPA1 mutations associated with dominant optic atrophy affect mitochondrial fusion and cell death in a domain-specific manner

GSE289826 Mus musculus Expression profiling by high throughput sequencing 15 samples 2025/02/24 GPL24247
Summary
Our study uncovered the role of OPA1 BSE domain in modulation of mitochondrial dynamics and cell death, and characterized the related signaling pathways, hereby providing the insight into the understanding of the domain-specific effect of OPA1 on mitochondrial morphology and function.
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NCBI GEO page ↗ Paper (PMID 40275276) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more mouse RNA-seq datasets →
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