GEO series
PolyA RNA seq of human glioblastoma cells treated with a pool of 11 miRNAs in vitro and in vivo (orthotopic tumors in mice)
GSE290046
Homo sapiens
Expression profiling by high throughput sequencing
22 samples
2025/10/29
GPL24676
Summary
Glioblastoma (GBM) has a poor prognosis due to infiltrative and therapy-resistant glioma stem-like cells. MicroRNAs (miRNAs) synergistically modulate biological pathways by repressing tumor-related genes, a mechanism lost in cancer. This study aimed to test a combination of different miRNAs exploiting their synergism as a multimodal therapy for GBM.
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Paper (PMID 41467122) ↗
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