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Enhancer-associated LncRNA-ITGA2 promotes vascular smooth muscle remodeling by mediating ITGA2 promoter-enhancer interactions [RNA-seq]

GSE290463 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2025/12/31 Platform GPL34284
Summary
To characterize the effects of PDGF-BB on long non-coding RNA (lncRNA) expression in vascular smooth muscle cells (VSMCs). Primary human VSMCs were cultured and treated with PDGF (20 ng/mL) or vehicle control (Veh) for 24 hours. Then we conducted lncRNA-seq and observed an increased in LncRNA-ITGA2 transcript reads following PDGF-BB treatment. This result is consistent with our microarray findings.
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Direct links to NCBI, no account and no request form: the whole study as GSE290463_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1225434 and SRA study SRP565691. Searching any of these in the dataset finder brings you back here.

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