GEO series
ChIP-seq of ESCC Cells Overexpressed TFAP2β or its LLPS-deficient Mutants
GSE290729
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
12 samples
2025/12/17
GPL29480
Summary
This dataset contains raw ChIP-seq data from esophageal squamous cell carcinoma (ESCC) cells overexpressing TFAP2β or its LLPS-deficient mutants (ΔIDR3 or Mut_IDR3). The experiment aims to explore the chromatin binding profiles of TFAP2β and its phase separation-deficient mutants to uncover the role of TFAP2β's LLPS activity in regulating gene expression in ESCC. Data were collected from the genomic binding of TFAP2β and its LLPS-deficient mutants, providing insights into the regulatory networks controlled by TFAP2β in cancer progression.
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Paper (PMID 41406964) ↗
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