Transcriptomic Analysis of Caco-2 Cells Co-cultured with KERP2-related Entamoeba histolytica Strains
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × Caco-2_wildtype_Trial vs 3 × Caco2_interacted_with_Entamoeba_histolytica_HA-KERP2_Trial vs 3 × Caco2_interacted_with_Entamoeba_histolytica_G3_Trial vs 3 × Caco2_interacted_with_Entamoeba_histolytica_KERP2gs_TrialGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- A multifaceted model of Entamoeba histolytica KERP2 regulating gene expression and host cell responsesNature communications · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE290901_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1230282 and SRA study SRP567183. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8825002 Caco-2_wildtype_Trial1 Caco-2_wildtype_Trial
- GSM8825003 Caco-2_wildtype_Trial2 Caco-2_wildtype_Trial
- GSM8825004 Caco-2_wildtype_Trial3 Caco-2_wildtype_Trial
- GSM8825005 Caco2_interacted_with_Entamoeba_histolytica_HA-KERP2_Trial1 Caco2_interacted_with_E…
- GSM8825006 Caco2_interacted_with_Entamoeba_histolytica_HA-KERP2_Trial2 Caco2_interacted_with_E…
- GSM8825007 Caco2_interacted_with_Entamoeba_histolytica_HA-KERP2_Trial3 Caco2_interacted_with_E…
- GSM8825008 Caco2_interacted_with_Entamoeba_histolytica_G3_Trial1 Caco2_interacted_with_E…
- GSM8825009 Caco2_interacted_with_Entamoeba_histolytica_G3_Trial2 Caco2_interacted_with_E…
- GSM8825010 Caco2_interacted_with_Entamoeba_histolytica_G3_Trial3 Caco2_interacted_with_E…
- GSM8825011 Caco2_interacted_with_Entamoeba_histolytica_KERP2gs_Trial1 Caco2_interacted_with_E…
- GSM8825012 Caco2_interacted_with_Entamoeba_histolytica_KERP2gs_Trial2 Caco2_interacted_with_E…
- GSM8825013 Caco2_interacted_with_Entamoeba_histolytica_KERP2gs_Trial3 Caco2_interacted_with_E…
- GSE46352 Caco-2 cells cultured in the presence of Lactobacillus fermentum strains AGR1485 or AGR1487 12 samples shares caco-2, strains
- GSE328863 Comparative transcriptomic points of departure analysis of pesticides in human Caco-2 and Hep G2 cells. 960 samples shares caco-2
- GSE23750 Role of REG 1 in Entamoeba histolytica colitis 16 samples shares histolytica, entamoeba
- GSE314628 Temporal Transcriptomic Profiling Identifies Core Regulators in Cytokine-Induced Gut Barrier Disruption in Differentiated Caco-2 Cells 73 samples shares caco-2
- GSE302559 Transcriptomic points of departure for 6PPD-Quinone derived from human Caco-2 and HepG2 cells 72 samples shares caco-2
- GSE276369 Comparative Analysis of Caco-2 Cells and Human Jejunal and Duodenal Enteroid-derived Cells in Gel- and Membrane-Based Barrier Models of Intestinal Permeability 13 samples shares caco-2
- GSE276364 Comparison of iPSC-derived human intestinal epithelial cells with Caco-2 cells and human in vivo data after exposure to Lactiplantibacillus plantarum WCFS1 36 samples shares caco-2
- GSE116213 Transcriptomic data of parent and NAPE-PLD deteled Caco-2 cells 4 samples shares caco-2
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.