Single-Cell Transcriptomic Profiling of the Tumor Microenvironment in Treatment-Naive Hepatocellular Carcinoma Patients

This study provides high-resolution single-cell RNA sequencing (scRNA-seq) data of tumor tissues from 12 treatment-naive hepatocellular carcinoma (HCC) patients. The dataset captures the transcriptomic profiles of diverse cell populations, including tumor cells, immune cells (e.g., T cells, B cells, macrophages), and stromal cells, revealing cellular heterogeneity and key gene expression signatures within the HCC tumor microenvironment (TME). This resource is critical for investigating HCC pathogenesis, identifying therapeutic targets, and developing immunotherapeutic strategies.