RNA-seq analyses of FOXF1/2- and p300/CBP-depleted senescent IMR-90 cells
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE291621_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1234523 and SRA study SRP569559. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 18 more — browse all 18 samples with per-sample file links →
- GSE239275 Investigate FOXA2, NKX2-1 and P300 regulated transcription program by RNA-seq in prostate cancer cells. 52 samples shares p300, rna-seq
- GSE245968 EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells (RNA-seq) 48 samples shares p300, rna-seq
- GSE307475 Bulk mRNA-seq analysis of IMR-90 SV40-T cells expressing wild-type and mutant H2B 18 samples shares imr-90, rna-seq
- GSE337503 RNA-seq analysis of CSNK2B and P300 knockdown in NCI-H69 small cell lung cancer cells 9 samples shares p300, rna-seq
- GSE255133 Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer (RNA-Seq) 32 samples shares p300, rna-seq
- GSE296237 Targeting p300/CBP abolishes HOXB13 loss-induced lipogenesis and tumor metastasis [RNA-seq] 28 samples shares p300, rna-seq
- GSE275778 AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer [RNA-seq: 22RV1] 20 samples shares p300, rna-seq
- GSE314447 Low physiological pH drives P300-mediated acetylation of PARP1 and promotes PARP inhibitor resistance [RNA-seq] 18 samples shares p300, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.