GEO series
Multi-omics analysis of brain metastasis elucidates obesity induced prostaglandin crosstalk in tumor microenvironment restrain CD8T cell expansion
GSE291804
Homo sapiens
Expression profiling by high throughput sequencing; Other
18 samples
2026/03/12
GPL24676
Summary
Brain metastasis (BrM) is one of the most crucial complications in tumor patients. Obesity contributes to the metabolic remodeling of tumor cells, yet the how obesity impact tumor microenvironment still remains unclear. We utilized scRNA-seq together with TCR seq to decipher the crosstalk with BrM microenvironment
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