The transcription factor IRF-5 is an essential metabolic checkpoint in CD8 T cells during chronic infection

Direct links to NCBI, no account and no request form: the whole study as GSE292794_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1241265 and SRA study SRP572819. Searching any of these in the dataset finder brings you back here.

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• GSE319035 P21+TREM2+-Senescent Macrophages Fuel Inflammaging and Metabolic Dysfunction-Associated Steatotic Liver Disease [NAFLD_time_course] 77 samples
• GSE278990 Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity 73 samples
• GSE300288 Single-cell and spatial transcriptomics analysis of tobacco-associated lung adenocarcinoma development, and in response to targeting inflammation alone or in combination with immune checkpoint blockade in precancerous phase [scRNA-seq] 31 samples
• GSE309993 Effector differentiation by stem-like intraepithelial γδ T cells is required for host defense against infection 25 samples
• GSE235046 Innate immune and metabolic signaling retain damaged mitochondria at cell membranes for mitoxyperilysis 15 samples
• GSE324432 A novel sorting method uncovers metabolic heterogeneity between mononucleated and binucleated tetraploid hepatocytes 15 samples
• GSE334497 TROP2/claudin program mediates immune exclusion to impede checkpoint blockade in breast cancer 10 samples
• GSE304706 Persistent ER stress in macrophages fuels age-related inflammation and vulnerability to infection 8 samples

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