GEO series
Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm.
GSE293151
Mus musculus
Expression profiling by high throughput sequencing
24 samples
2025/07/21
GPL34290
Summary
We discovered a role for the transcription factor OTX2 in formation of mouse definitive endoderm (DE). We used RNAseq to measure changes in gene expression and identify OTX2-regulated genes during directed differentiation of EpiSCs to Primitive Streak (PS) intermediates and DE
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Paper (PMID 40834858) ↗
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