GEO series
RNA-seq of ESCC Cells Overexpressed TFAP2β or its LLPS-deficient Mutants
GSE293553
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/12/17
GPL34284
Summary
This dataset contains raw RNA-seq data from esophageal squamous cell carcinoma (ESCC) cells overexpressing GFP-TFAP2β, its LLPS-deficient mutants (ΔIDR3 and Mut_IDR3) or GFP control. The experiment aims to explore the downstream genes of TFAP2β and its phase separation-deficient mutants to uncover the role of TFAP2β's LLPS activity in regulating gene expression in ESCC. Data were collected from the genomic binding of TFAP2β and its LLPS-deficient mutants, providing insights into the regulatory networks controlled by TFAP2β in cancer progression.
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Paper (PMID 41406964) ↗
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