BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis [ChIP-Seq 1]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 4 × Young_H3K4me3_ChIP vs 4 × Old_H3K4me3_ChIP vs 4 × Young_H3K4me3_input vs 4 × Old_H3K4me3_inputGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294069_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1247992 and SRA study SRP577254. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8898262 Young_H3K4me3_ChIP_1 Young_H3K4me3_ChIP
- GSM8898263 Young_H3K4me3_ChIP_2 Young_H3K4me3_ChIP
- GSM8898264 Young_H3K4me3_ChIP_3 Young_H3K4me3_ChIP
- GSM8898265 Young_H3K4me3_ChIP_4 Young_H3K4me3_ChIP
- GSM8898266 Old_H3K4me3_ChIP_1 Old_H3K4me3_ChIP
- GSM8898267 Old_H3K4me3_ChIP_2 Old_H3K4me3_ChIP
- GSM8898268 Old_H3K4me3_ChIP_3 Old_H3K4me3_ChIP
- GSM8898269 Old_H3K4me3_ChIP_4 Old_H3K4me3_ChIP
- GSM8898270 Young_H3K4me3_input_1 Young_H3K4me3_input
- GSM8898271 Young_H3K4me3_input_2 Young_H3K4me3_input
- GSM8898272 Young_H3K4me3_input_3 Young_H3K4me3_input
- GSM8898273 Young_H3K4me3_input_4 Young_H3K4me3_input
- GSM8898274 Old_H3K4me3_input_1 Old_H3K4me3_input
- GSM8898275 Old_H3K4me3_input_2 Old_H3K4me3_input
- GSM8898276 Old_H3K4me3_input_3 Old_H3K4me3_input
- GSM8898277 Old_H3K4me3_input_4 Old_H3K4me3_input
- GSM8898278 Old_H3K27ac_ChIP
- GSM8898279 Young_H3K27ac_ChIP
- GSM8898280 Old_H3K4me1_ChIP
- GSM8898281 Young_H3K4me1_ChIP
- GSE294070 BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis [ChIP-Seq 2] 15 samples shares bmal1, yap, cooperate, enhancers, epidermis, chip-seq, promote, hijack
- GSE294389 BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis 131 samples shares bmal1, yap, cooperate, enhancers, epidermis, promote, hijack
- GSE294336 BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis [RNA-seq Aged_adult] 48 samples shares bmal1, yap, cooperate, enhancers, epidermis, promote, hijack
- GSE294339 BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis [RNA-seq Col14] 48 samples shares bmal1, yap, cooperate, enhancers, epidermis, promote, hijack
- GSE300774 H3K9me3 controls epidermis development by repressing RNA Pol II activity on key promoters and enhancers 34 samples shares enhancers, epidermis, promote
- GSE277188 Decoding the YAP/TAZ–PPARγ Regulatory Axis in Adipocyte Differentiation and Dedifferentiation [ChIP-seq] 46 samples shares yap, chip-seq
- GSE274930 ZMAT1 promotes osteoclast formation and bone loss through TRIM46 mediated YAP1 degradation II 18 samples shares yap, promote
- GSE327565 Sustained Yap/Taz activation promotes aberrant alveolar epithelial cell differentiation and drives persistent fibrotic remodeling 14 samples shares yap, promote
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.