NDF/GLYR1 Promotes RNA Polymerase II Processivity via Pol II Binding and Nucleosome Destabilization
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 15 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 15 samples: 12 distinct titles, 3 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- NDF/GLYR1 Promotes RNA Polymerase II Processivity via Pol II Binding and Nucleosome DestabilizationInternational journal of molecular sciences · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294087_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1248047 and SRA study SRP577287. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 15 sample titles: 12 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8898465 Hela NDF-WT, Pol II, ChIP_DRB_0min
- GSM8898466 Hela NDF-WT, Pol II, ChIP_DRB_5min
- GSM8898467 Hela NDF-WT, Pol II, ChIP_DRB_10min
- GSM8898468 Hela NDF-WT, Pol II, ChIP_DRB_20min
- GSM8898469 Hela NDF-KO, Pol II, ChIP_DRB_0min
- GSM8898470 Hela NDF-KO, Pol II, ChIP_DRB_5min
- GSM8898471 Hela NDF-KO, Pol II, ChIP_DRB_10min
- GSM8898472 Hela NDF-KO, Pol II, ChIP_DRB_20min
- GSM8898473 SW480 NDF-KO, WT_Rescue, NDF, ChIP_Rep1
- GSM8898474 SW480 NDF-KO, WT_Rescue, NDF, ChIP_Rep2
- GSM8898475 SW480 NDF-KO, MT2_Rescue, NDF, ChIP_Rep1
- GSM8898476 SW480 NDF-KO, MT2_Rescue, NDF, ChIP_Rep2
- GSM8898477 SW480 NDF-KO, MT4_Rescue, NDF, ChIP_Rep1
- GSM8898478 SW480 NDF-KO, MT4_Rescue, NDF, ChIP_Rep2
- GSM8898479 SW480 NDF-KO, WT_Rescue, NDF, ChIP_Input
- GSE316977 Mithramycin Alters EWS::FLI1 DNA Binding and RNA Polymerase II Processivity to Inhibit Nascent Transcription [CUT&Tag] 16 samples shares processivity, polymerase, binding
- GSE305545 Mithramycin Alters EWS::FLI1 DNA Binding and RNA Polymerase II Processivity to Inhibit Nascent Transcription 11 samples shares processivity, polymerase, binding
- GSE316978 Mithramycin Alters EWS::FLI1 DNA Binding and RNA Polymerase II Processivity to Inhibit Nascent Transcription [RNA-seq] 9 samples shares processivity, polymerase, binding
- GSE273681 NDF-FACT phase separation condensates are required for RNA Polymerase II transcription elongation through chromatin [RNA-Seq] 12 samples shares ndf, polymerase
- GSE288755 eIF2D promotes 40S ribosomal subunit recycling during intrinsic ribosome destabilization 52 samples shares destabilization, promotes
- GSE186090 LncRNA EIF1AX-AS1 promotes endometrial cancer cell apoptosis via interacting with PCBP1 to facilitate EIF1AX mRNA destabilization 4 samples shares destabilization, promotes
- GSE273678 Phase-separated NDF−FACT condensates facilitate transcription elongation on chromatin [ChIP-Seq] 55 samples shares ndf
- GSE273679 Phase-separated NDF−FACT condensates facilitate transcription elongation on chromatin [CUT&Run] 11 samples shares ndf
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.