Enhanced activities of OCT4 and SOX2 facilitates epigenetic reprogramming by modulating cell cycle [OSK/OvSvK CUT&TAG]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 11 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 5 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 PhaseAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294288_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1248943 and SRA study SRP578038. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 5 replicated groups read from 11 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8901780 OSK Day3 CUT&Tag-seq of H3K27ac rep1 OSK Day3 CUT&Tag-seq of…
- GSM8901781 OvSvK Day2 CUT&Tag-seq of H3K27ac rep1 OvSvK Day2 CUT&Tag-seq …
- GSM8901782 OSK Day3 CUT&Tag-seq of Oct4 rep1
- GSM8901783 OvSvK Day2 CUT&Tag-seq of Oct4 rep1 OvSvK Day2 CUT&Tag-seq …
- GSM8901784 OSK Day3 CUT&Tag-seq of Sox2 rep1 OSK Day3 CUT&Tag-seq of…
- GSM8901785 OvSvK Day2 CUT&Tag-seq of Sox2 rep1 OvSvK Day2 CUT&Tag-seq …
- GSM8901786 OSK Day3 CUT&Tag-seq of H3K27ac rep2 OSK Day3 CUT&Tag-seq of…
- GSM8901787 OvSvK Day2 CUT&Tag-seq of H3K27ac rep2 OvSvK Day2 CUT&Tag-seq …
- GSM8901788 OvSvK Day2 CUT&Tag-seq of Oct4 rep2 OvSvK Day2 CUT&Tag-seq …
- GSM8901789 OSK Day3 CUT&Tag-seq of Sox2 rep2 OSK Day3 CUT&Tag-seq of…
- GSM8901790 OvSvK Day2 CUT&Tag-seq of Sox2 rep2 OvSvK Day2 CUT&Tag-seq …
- GSE279042 Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing [CUT&Tag] 30 samples shares cut, tag, reprogramming
- GSE304211 H4K16ac contributes to chromatin compartment reorganization during mitotic and meiotic transitions [CUTnTAG] 128 samples shares cut, tag
- GSE297309 SKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced gene [CUT&Tag] 108 samples shares cut, tag
- GSE325799 KMT2C and KMT2D amplify GRHL2-driven enhancer activation [CUT&Tag] 80 samples shares cut, tag
- GSE298418 MeCP2 stabilizes the glucocorticoid system in active chromatin regions [CUT&Tag] 63 samples shares cut, tag
- GSE336091 KMT2C catalytic activity regulates enhancer H3K4me1 and synaptic gene expression in cortical excitatory neurons [CUT&Tag] 48 samples shares cut, tag
- GSE274493 The remodeling of bivalent chromatin is essential for mouse peri-implantation embryogenesis [CUT&Tag] 46 samples shares cut, tag
- GSE264614 Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in mouse early embryos [ATAC-seq] 44 samples shares oct4, sox2
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.