GEO series
Cutaneous lupus features specialized stromal niches and altered retroelement expression
GSE294296
Homo sapiens
Other; Expression profiling by high throughput sequencing
16 samples
2025/04/14
GPL24676
Summary
Single-cell RNA and spatial sequencing of lesional and non-lesional cutaneous lupus skin compared to healthy controls. The study includes 12 single-cell samples (cutaneous lupus patients with non-lesional (5) and lesional (4) skin biopsies with healthy controls (3)) and 4 spatial transcriptomics samples (cutaneous lupus patient pre/post-Anifrolumab treatment, 1 additional CLE patient, and 1 healthy control).
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Paper (PMID 42199555) ↗
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