Proton-secreting cells modulate mucosal immune surveillance in the male reproductive tract
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 18 × FBb1Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Proton-Secreting Cells as Drivers of Inflammation and Sperm Dysfunction in LPS-Induced EpididymitisFunction (Oxford, England) · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294713_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1251360 and SRA study SRP578964. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 1 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8917657 FBb1-1 FBb1
- GSM8917658 FBb1-2 FBb1
- GSM8917659 FBb1-3 FBb1
- GSM8917660 FBb1-4 FBb1
- GSM8917661 FBb1-5 FBb1
- GSM8917662 FBb1-6 FBb1
- GSM8917663 FBb1-7 FBb1
- GSM8917664 FBb1-8 FBb1
- GSM8917665 FBb1-9 FBb1
- GSM8917666 FBb1-10 FBb1
- GSM8917667 FBb1-11 FBb1
- GSM8917668 FBb1-12 FBb1
- GSM8917669 FBb1-13 FBb1
- GSM8917670 FBb1-14 FBb1
- GSM8917671 FBb1-15 FBb1
- GSM8917672 FBb1-16 FBb1
- GSM8917673 FBb1-17 FBb1
- GSM8917674 FBb1-18 FBb1
- GSE269257 A lack of commensal microbiota influences the male reproductive tract intergenerationally in mice 62 samples shares reproductive, tract, male
- GSE305066 The postcopulatory transcriptional response in different sections of the female reproductive tract 39 samples shares reproductive, tract, male
- GSE297609 NK cells in the female reproductive tract (FRT) acquire an effector transcriptional program during menstruation 19 samples shares reproductive, tract, male
- GSE158473 Exposure to di(2-ethylhexyl) phthalate and diisononyl phthalate during adulthood disrupts hormones and ovarian folliculogenesis throughout the prime reproductive life of the female mouse. 30 samples shares reproductive, male
- GSE241318 Asynchronous female reproductive organ ageing as revealed by single-cell transcriptomic atlas 21 samples shares reproductive, male
- GSE325001 Gut microbiota-modulated glutamic acid rejuvenates the quality of oocytes deteriorated by advanced reproductive age [RNAseq-FMT] 20 samples shares reproductive, modulate
- GSE325162 Gut microbiota-modulated glutamic acid rejuvenates the quality of oocytes deteriorated by advanced reproductive age 69 samples shares reproductive, modulate
- GSE274902 Mogat1 drives metabolic adaptations to evade immune surveillance 32 samples shares surveillance
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.