Identification of recurrent tumor-specific markers in patient-matched ovarian cancer samples
RNA-seq (gene expression) · human · 48 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Ovarian cancerThis series is part of our curated briefing on it.
- Samples
- 48 samples: 24 × ovary, primary, patient vs 24 × ovary, recurrent, patientGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Integrative Multi-Omics Analysis Reveals Molecular Signatures of Recurrence in Paired Primary and Recurrent High-Grade Serous Ovarian CancerInternational journal of molecular sciences · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE295041_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1252700 and SRA study SRP579686. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 48 samples.
How we read this: 2 replicated groups read from 48 sample titles; they account for 48 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8941009 ovary, primary, patient1 ovary, primary, patient
- GSM8941010 ovary, primary, patient2 ovary, primary, patient
- GSM8941011 ovary, primary, patient3 ovary, primary, patient
- GSM8941012 ovary, primary, patient4 ovary, primary, patient
- GSM8941013 ovary, primary, patient5 ovary, primary, patient
- GSM8941014 ovary, primary, patient6 ovary, primary, patient
- GSM8941015 ovary, primary, patient7 ovary, primary, patient
- GSM8941016 ovary, primary, patient8 ovary, primary, patient
- GSM8941017 ovary, primary, patient9 ovary, primary, patient
- GSM8941018 ovary, primary, patient10 ovary, primary, patient
- GSM8941019 ovary, primary, patient11 ovary, primary, patient
- GSM8941020 ovary, primary, patient12 ovary, primary, patient
- GSM8941021 ovary, primary, patient13 ovary, primary, patient
- GSM8941022 ovary, primary, patient14 ovary, primary, patient
- GSM8941023 ovary, primary, patient15 ovary, primary, patient
- GSM8941024 ovary, primary, patient16 ovary, primary, patient
- GSM8941025 ovary, primary, patient17 ovary, primary, patient
- GSM8941026 ovary, primary, patient18 ovary, primary, patient
- GSM8941027 ovary, primary, patient19 ovary, primary, patient
- GSM8941028 ovary, primary, patient20 ovary, primary, patient
- GSM8941029 ovary, primary, patient21 ovary, primary, patient
- GSM8941030 ovary, primary, patient22 ovary, primary, patient
- GSM8941031 ovary, primary, patient23 ovary, primary, patient
- GSM8941032 ovary, primary, patient24 ovary, primary, patient
- GSM8941033 ovary, recurrent, patient1 ovary, recurrent, patie…
- GSM8941034 ovary, recurrent, patient2 ovary, recurrent, patie…
- GSM8941035 ovary, recurrent, patient3 ovary, recurrent, patie…
- GSM8941036 ovary, recurrent, patient4 ovary, recurrent, patie…
- GSM8941037 ovary, recurrent, patient5 ovary, recurrent, patie…
- GSM8941038 ovary, recurrent, patient6 ovary, recurrent, patie…
- GSM8941039 ovary, recurrent, patient7 ovary, recurrent, patie…
- GSM8941040 ovary, recurrent, patient8 ovary, recurrent, patie…
- GSM8941041 ovary, recurrent, patient9 ovary, recurrent, patie…
- GSM8941042 ovary, recurrent, patient10 ovary, recurrent, patie…
- GSM8941043 ovary, recurrent, patient11 ovary, recurrent, patie…
- GSM8941044 ovary, recurrent, patient12 ovary, recurrent, patie…
- GSM8941045 ovary, recurrent, patient13 ovary, recurrent, patie…
- GSM8941046 ovary, recurrent, patient14 ovary, recurrent, patie…
- GSM8941047 ovary, recurrent, patient15 ovary, recurrent, patie…
- GSM8941048 ovary, recurrent, patient16 ovary, recurrent, patie…
+ 8 more — browse all 48 samples with per-sample file links →
- GSE268514 Integrative genomic analysis of Korean high-grade serous ovarian cancer 161 samples same disease briefing · shares ovarian
- GSE311212 Transcriptomic profiling in human ovarian cancer cell line OVCAR-3 following CDK2 inhibitor treatment 6 samples same disease briefing · shares ovarian
- GSE128098 TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target 4 samples same disease briefing · shares ovarian
- GSE154600 Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma 5 samples same disease briefing · shares ovarian
- GSE57477 Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes 72 samples same disease briefing · shares ovarian
- GSE314300 Rb CUT&RUN profiling in ovarian cancer cell lines following CDK2 inhibitor treatment 10 samples same disease briefing · shares ovarian
- GSE135242 Hi-C identifies structural variation associated with resistance in paired patient-derived ovarian cancer models 8 samples same disease briefing · shares ovarian
- GSE28330 Telomeric Allelic Imbalance Indicates Defective DNA Repair and Sensitivity to DNA-Damaging Agents 107 samples same disease briefing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.