KLF5 interacts with RUVBL1/2 to activate classical and basal lineage identities in PDAC [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 138 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 138 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- KLF5 enables dichotomous lineage programs in pancreatic cancer via the AAA+ ATPase coactivators RUVBL1 and RUVBL2Nature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE295354_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1254253 and SRA study SRP580623. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 138 more — browse all 138 samples with per-sample file links →
- GSE295349 KLF5 interacts with RUVBL1/2 to activate classical and basal lineage identities in PDAC [RNA-seq] 183 samples shares ruvbl1, klf5, pdac, identities, interacts, classical, activate
- GSE295347 KLF5 interacts with RUVBL1/2 to activate classical and basal lineage identities in PDAC [SLAM-seq] 62 samples shares ruvbl1, klf5, pdac, identities, interacts, classical, activate
- GSE301284 KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival [ChIP-Seq] 46 samples shares klf5, chip-seq
- GSE243951 KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma [ChIP-seq] 6 samples shares klf5, chip-seq
- GSE310807 KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival 21 samples shares klf5
- GSE272459 Chromatin landscape analysis of pancreatic progenitor organoids (POs) bearing PDAC related mutations [ATAC] 16 samples shares pdac
- GSE272463 Chromatin Landscape Analysis of Patient PDAC 14 samples shares pdac
- GSE312769 RUVBL1 and RUVBL2 are druggable MYCN regulators in neuroblastoma 13 samples shares ruvbl1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.