GEO series
Single-cell sequencing of human PBMCs are exposure to CPMV
GSE295467
Homo sapiens
Expression profiling by high throughput sequencing
48 samples
2026/03/04
GPL34284
Summary
Cowpea mosaic virus (CPMV) is a potent immunomodulator with anti-tumor function. CPMV is being developed as an intratumoral immunotherapy candidate for clinical translation. A fundamental question is understanding how CPMV modulates the immune system through genetic/transcriptomic changes. This experiment outlines how CPMV exposure reprograms immune cells toward anti-neoplastic functions.
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Paper (PMID 41737598) ↗
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