CXCR4-LASP1-G9a-SNAIL Axis Drives NEPC Transdifferentiation via Induction of EMT and Downregulation of REST
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- CXCR4-LASP1-G9a-SNAIL axis drives NEPC transdifferentiation via induction of EMT and downregulation of RESTCell genomics · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE296570_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1259987 and SRA study SRP583708. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE145327 Loss of extreme long-range enhancers in human neural crest drives a craniofacial disorder 80 samples shares rest, drives
- GSE263717 Epigenomic profiles of SLE resting and transitional B cells 150 samples shares rest
- GSE242143 DNA methylation status determines the sensitivity of repeats to restriction by the HUSH-MORC2 complex 75 samples shares rest
- GSE261846 ARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial to mesenchymal transition in cranial neural crest lineage commitment. 74 samples shares rest
- GSE278549 PBAF associates with repressed chromatin to enable REST occupancy 61 samples shares rest
- GSE288669 CHD3 regulates BMP signalling response during cranial neural crest cell specification 56 samples shares rest
- GSE293821 SALL4 recruits BAF to activate enhancers required for cranial neural crest cell specification 26 samples shares rest
- GSE302154 Restoring Taxane Efficacy in Castration Resistant Prostate Cancer Through Targeting Menin 20 samples shares rest
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.