Therapeutic potential of heat-killed Enterococcus faecalis (EC-12) Para-Probiotic in reversing maternal separation-triggered social deficit in Mice
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE296684_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1258552 and SRA study SRP583404. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 21 samples.
How we read this: 6 replicated groups read from 24 sample titles; they account for 21 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8974613 prefrontal cortex , control group ,rep 1 prefrontal cortex , con…
- GSM8974614 prefrontal cortex , control group, rep 2 prefrontal cortex , con…
- GSM8974615 prefrontal cortex , control group ,rep 3 prefrontal cortex , con…
- GSM8974616 prefrontal cortex , control group, rep4 prefrontal cortex , con…
- GSM8974617 prefrontal cortex , control group,rep5 prefrontal cortex , con…
- GSM8974618 prefrontal cortex , control group,rep6 prefrontal cortex , con…
- GSM8974619 prefrontal cortex ,MS group ,rep1 prefrontal cortex ,MS g…
- GSM8974620 prefrontal cortex ,MS group ,rep2 prefrontal cortex ,MS g…
- GSM8974621 prefrontal cortex , MS group ,rep 3 prefrontal cortex , MS …
- GSM8974622 prefrontal cortex , MS group ,rep 4 prefrontal cortex , MS …
- GSM8974623 prefrontal cortex , MS group ,rep 5 prefrontal cortex , MS …
- GSM8974624 prefrontal cortex , MS group ,rep 6 prefrontal cortex , MS …
- GSM8974625 prefrontal cortex , Control_EC12 group ,rep 1
- GSM8974626 prefrontal cortex , Control_EC12group ,rep 2
- GSM8974627 prefrontal cortex , Control_EC12group ,rep 3 prefrontal cortex , Con…
- GSM8974628 prefrontal cortex , Control_EC12group ,rep 4 prefrontal cortex , Con…
- GSM8974629 prefrontal cortex , Control_EC12group,rep 5
- GSM8974630 prefrontal cortex , Control_EC12group ,rep 6 prefrontal cortex , Con…
- GSM8974631 prefrontal cortex ,MS_EC12 group ,rep 1 prefrontal cortex ,MS_E…
- GSM8974632 prefrontal cortex ,MS_EC12 group ,rep 2 prefrontal cortex ,MS_E…
- GSM8974633 prefrontal cortex ,MS_EC12 group ,rep 3 prefrontal cortex ,MS_E…
- GSM8974634 prefrontal cortex ,MS_EC12 group ,rep 4 prefrontal cortex ,MS_E…
- GSM8974635 prefrontal cortex ,MS_EC12 group ,rep 5 prefrontal cortex ,MS_E…
- GSM8974636 prefrontal cortex ,MS_EC12 group ,rep 6 prefrontal cortex ,MS_E…
- GSE188916 Enterococcus faecalis-derived lactate mediated suppression of NF-κB and ERK pathways in macrophages to promote polymicrobial wound infection 24 samples shares enterococcus
- GSE284676 Enterococcus faecium activates BMP/SMAD-mediated osteoblastogenesis and Wnt mediated neurogenesis while inhibiting PD 15 samples shares enterococcus
- GSE242865 Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis 6 samples shares enterococcus
- GSE229257 Gene expression profile at single cell level from untreated and Enterococcus faecalis-infected skin wounds 4 samples shares enterococcus
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.