← BioTransfer GEO Dataset Finder
GEO series

Targeting HDAC8 sensitizes tyrosine kinase inhibitors in the elimination of B-cell acute lymphoblastic leukemia cells through degradation of HIF-1α

GSE296685 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/06/05 Platform GPL24676
Summary
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to analysis the differiational genes and pathways in Ph+ B-ALL cells treated with control, dasatinib, or 22d+dasatinib.
Published in
Targeting HDAC8 sensitizes tyrosine kinase inhibitors in the elimination of B-cell acute lymphoblastic leukemia cells through degradation of HIF-1α
Xu G, Wang F, Chen M et al. · Leukemia 2025 · PMID 40897850 · doi:10.1038/s41375-025-02749-6
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE296685_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1260531 and SRA study SRP583960. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 9 more — browse all 9 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.