Metabolic regulation of host defense against influenza virus infection through sensing oxaloacetate
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × Vehicle vs 3 × Vehicle-H1N1 vs 3 × DEOAA vs 3 × DEOAA-H1N1Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297098_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1262515 and SRA study SRP585014. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8983688 Vehicle-1 Vehicle
- GSM8983689 Vehicle-2 Vehicle
- GSM8983690 Vehicle-3 Vehicle
- GSM8983691 Vehicle-H1N1-1 Vehicle-H1N1
- GSM8983692 Vehicle-H1N1-2 Vehicle-H1N1
- GSM8983693 Vehicle-H1N1-3 Vehicle-H1N1
- GSM8983694 DEOAA-1 DEOAA
- GSM8983695 DEOAA-2 DEOAA
- GSM8983696 DEOAA-3 DEOAA
- GSM8983697 DEOAA-H1N1-1 DEOAA-H1N1
- GSM8983698 DEOAA-H1N1-2 DEOAA-H1N1
- GSM8983699 DEOAA-H1N1-3 DEOAA-H1N1
- GSE299820 Innate immune epigenomic landscape following controlled human influenza virus infection 755 samples shares influenza, virus
- GSE283403 Influenza virus exposure shapes the B cell response to influenza vaccination fifty years later 90 samples shares influenza, virus
- GSE313190 Cell-free RNA reveals host and microbial correlates of broadly neutralizing antibody development against HIV 56 samples shares against, host
- GSE294890 Soluble uric acid suppresses neutrophil-mediated host defense in sepsis 30 samples shares defense, host
- GSE334767 Human keratinocytes and fibroblasts coordinate early cutaneous innate defense against Candida auris 24 samples shares defense, against
- GSE280966 RNA-Seq Analysis to investigate the impact of hypoxia on the host responses to Nontypeable Haemophilus influenzae infection in the human explanted lung 20 samples shares influenza, host
- GSE226633 B cell convergence to distinct broadly reactive epitopes following vaccination with chimeric influenza virus hemagglutinins 19 samples shares influenza, virus
- GSE186299 Comparative Analysis of Transcriptional RNA Expression in HEK293T Cells Transfected with the H3N2 Subtype Canine Influenza Viruses M1/M2 and Canine RIG-I 15 samples shares influenza, virus
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.