GEO series
The effect of knockdown FAM111B on mRNA expression in human hepatocellular carcinoma cells
GSE297369
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/05/23
GPL20301
Summary
Family with sequence similarity 111 member B (FAM111B) encodes a protein with a trypsin-like cysteine/serine peptidase domain, the aberrant expression of which has been observed to contribute to malignant behavior and poor prognosis of various cancers, such as hepatocellular carcinoma (HCC), thyroid cancer, esophageal cancer, ovarian cancer, and lung adenocarcinoma. Previous studies described the role of FAM111B as a prognostic predictor or a potential protease that may degrade certain tumor suppressor. Our data demonstrated regulatory changes at the genomic transcriptional level after interfering FAM111B expression in HCC.
Download
NCBI GEO page ↗
Paper (PMID 40855067) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
human RNA-seq datasets →
Similar datasets
- GSE328275 Single-cell RNA sequencing of CD45+ immune cells across primary tumor, sentinel tumor-draining lymph node, and axillary lymph node in treatment-naive triple-negative breast cancer 28 samples
- GSE341753 Cohesin loading at regulatory elements shapes 3D genome folding during erythropoiesis [RNA-Seq] 12 samples
- GSE319969 Spatial and Bulk Transcriptomic Profiling Defines the Molecular Evolution of Cutaneous Squamous Cell Carcinoma and Reveals Stage-Specific Biomarkers of Clinical Relevance [RNA-Seq] 24 samples
- GSE313035 METIMMOX: Colorectal Cancer METastasis - Shaping Anti-tumor IMMunity by OXaliplatin 67 samples
- GSE342462 Integrated transcriptomic and bioelectrical profiling of stem-like cellular states in a colorectal cancer using SdFFF and UHF-DEP 12 samples
- GSE339456 Integrated bulk and spatial transcriptomic analysis identifies progression-associated molecular signatures in biopsy-proven hypertensive nephropathy [RNA-seq] 35 samples
- GSE199939 Comprehensive transcriptomic analysis of immune-related genes in diabetic foot ulcers: New insights into mechanisms and therapeutic targets 21 samples
- GSE341139 A conserved HAND2-BMP5-SMAD1/5/9 axis drives hepatic stellate cell activation and extracellular matrix overproduction in multiple fibrotic etiologies 10 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.