Loss of age-associated increase in m6A-modified RNA contributes to GABAergic dysregulation in Alzheimer’s disease
RNA-seq (gene expression) · human · 60 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 60 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297551_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1265180 and SRA study SRP586355. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 60 more — browse all 60 samples with per-sample file links →
- GSE311483 BAP1 dysregulation impairs trophoblast differentiation and contributes to placental dysfunction in preeclampsia 32 samples shares dysregulation, contributes
- GSE327021 Ubiquitin-Proteasome System Dysregulation in Alzheimer's Disease Impacts Protein Abundance 24 samples shares dysregulation, alzheimer
- GSE338264 Loss of cellular RNA homeostasis contributes to MDA5 activation during virus infection 22 samples shares contributes, loss
- GSE304101 Loss of ATM causes R-loop-associated transcriptional dysregulation and attenuates the related response to DNA damage [RNA-Seq] 18 samples shares dysregulation, loss
- GSE308999 Dysregulation of RNA Editing Contributes to Platinum Resistance in Ovarian Cancer 14 samples shares dysregulation, contributes
- GSE270454 Epigenetic dysregulation of transposable elements in cognitive impairment and Alzheimer’s disease 135 samples shares dysregulation, alzheimer
- GSE304105 Loss of ATM causes R-loop-associated transcriptional dysregulation and attenuates the related response to DNA damage [DRIP-Seq] 30 samples shares dysregulation, loss
- GSE271896 Deep longitudinal immune profiling reveals reprogramming of memory T cells that links to B cell dysregulation with age 868 samples shares dysregulation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.