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scRNAseq analysis of 8 week-old KPPC WT, MAP3K7ff KPPC and MAP3K7fwt KPPC mice pancreatic tumor

GSE297618 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2026/02/05 Platform GPL19057
Summary
We pooled three 8 week-old KPPC WT (n=3), MAP3K7ff KPPC (n=3) and MAP3K7fwt KPPC (n=3) mice pancreatic tumor respectively into one sample, prepared single cell suspension and performed 10X genomics scRNASeq to assess transcriptomic changes all cell populations
Published in
Targeting tumor-intrinsic TAK1 triggers anti-tumor immunity and sensitizes pancreatic cancer to checkpoint blockade
Bansod SP, Chen TH, Somani VK et al. · bioRxiv : the preprint server for biology 2025 · PMID 41280086 · doi:10.1101/2025.10.08.681226
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Direct links to NCBI, no account and no request form: the whole study as GSE297618_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1265272 and SRA study SRP586409. Searching any of these in the dataset finder brings you back here.

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