BRRIAR lncRNA alters breast cancer risk by modulating interferon signaling in cis and in trans through BHLHE40 and RIG-I [RNA-Seq]
RNA-seq (gene expression) · human · 27 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Breast cancerThis series is part of our curated briefing on it.
- Samples
- 27 samples: 27 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- BRRIAR lncRNA alters breast cancer risk by modulating interferon signaling in cis and in transMolecular cancer · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297682_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1265681 and SRA study SRP586616. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 27 sample titles: 27 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8996628 DsiCON1_S1
- GSM8996629 DsiCON2_S2
- GSM8996630 DsiCON3_S3
- GSM8996631 DsiBRIAR1_S4
- GSM8996632 DsiBRIAR2_S5
- GSM8996633 DsiBRIAR3_S6
- GSM8996634 DsiBRIAR4_S7
- GSM8996635 DsiBRIAR5_S8
- GSM8996636 DsiBRIAR6_S9
- GSM8996637 AA20162_CTRL
- GSM8996638 AA20174_CTRL
- GSM8996639 AA20227_CTRL
- GSM8996640 AA20341_SG1A
- GSM8996641 AA20480_SG1B
- GSM8996642 AA20484_SG1C
- GSM8996643 AA20594_SG2A
- GSM8996644 AA20853_SG2B
- GSM8996645 AA20856_SG2C
- GSM8996646 AA34059_CTRL
- GSM8996647 AA34061_CTRL
- GSM8996648 AA34062_CTRL
- GSM8996649 AA34064_SG1A
- GSM8996650 AA34066_SG1B
- GSM8996651 AA34067_SG1C
- GSM8996652 AA34068_SG2A
- GSM8996653 AA34069_SG2B
- GSM8996654 AA34070_SG2C
- GSE104193 Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signalling and malignant features in vitro and in vivo 32 samples same disease briefing
- GSE104675 Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 6 samples same disease briefing
- GSE10885 An integromic analysis reveals that metaplastic carcinomas are distinct from basal-like tumors. 244 samples same disease briefing
- GSE10886 A Supervised Risk Predictor of Breast Cancer Based on Biological Subtypes 226 samples same disease briefing
- GSE11121 The humoral immune system has a key prognostic impact in node-negative breast cancer 200 samples same disease briefing
- GSE305885 BRRIAR lncRNA alters breast cancer risk by modulating interferon signaling in cis and in trans through BHLHE40 and RIG-I 6 samples shares bhlhe40, brriar, rig-i, modulating, interferon, lncrna, alters
- GSE93071 Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [RNA-Seq] 12 samples shares rig-i, rna-seq
- GSE300850 The role of RUNX2 and BHLHE40 in pathologically relevant CD4-positive tissue-resident T-cells in Crohn's disease. (RNA-seq, CD4+ T cell, part2) 6 samples shares bhlhe40, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.