Free-floating Long-term Vascularized Mesenchymal Organoids [RNA-seq]
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 20 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Free-floating long-term vascularized mesenchymal organoidsiScience · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297746_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1266109 and SRA study SRP587447. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 20 sample titles: 20 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8998320 Organoid Day 3 - A
- GSM8998321 Organoid Day 3 - B
- GSM8998322 Organoid Day 3 - C
- GSM8998323 Organoid Day 3 - D
- GSM8998324 Organoid Day 14 - A
- GSM8998325 Organoid Day 14 - B
- GSM8998326 Organoid Day 14 - C
- GSM8998327 Organoid Day 14 - D
- GSM8998328 Organoid Day 28 - A
- GSM8998329 Organoid Day 28 - B
- GSM8998330 Organoid Day 28 - C
- GSM8998331 Organoid Day 28 - D
- GSM8998332 Organoid Day 60 - A
- GSM8998333 Organoid Day 60 - B
- GSM8998334 Organoid Day 60 - C
- GSM8998335 Organoid Day 60 - D
- GSM8998336 Spheroid Day 14 - A
- GSM8998337 Spheroid Day 14 - B
- GSM8998338 Spheroid Day 14 - C
- GSM8998339 Spheroid Day 14 - D
- GSE234181 Long-term multi-modal recording reveals epigenetic adaptation routes in dormant breast cancer cells [scRNA-Seq] 184 samples shares long-term, rna-seq
- GSE348445 Identification and Characterization of Adrenergic and Mesenchymal Cancer Cell States in Neuroblastoma Using Spatial-Omics [RNA-Seq] 33 samples shares mesenchymal, rna-seq
- GSE301846 co-cultures of mesenchymal cells with epithelial organoids promote fusion into bioengineered liver tissues by ECM remodeling 31 samples shares mesenchymal, organoids
- GSE217649 Bulk RNA sequencing for gene expression profileing of primary liver sinusoidal endothelial cells and iPSC-derived hepatic endoderm, septum mesenchymal cells, endothelial cells, and liver bud organoids 26 samples shares mesenchymal, organoids
- GSE298576 Mass generation and long-term expansion of hepatocyte organoids from adult primary hepatocytes 24 samples shares long-term, organoids
- GSE278450 Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells 22 samples shares mesenchymal, rna-seq
- GSE298139 Therapy-resistance in AT/RT is driven by epithelial-mesenchymal transition, extracellular matrix changes, and enrichment of CD1A+ CD207+ dendritic cells [snRNA-seq] 16 samples shares mesenchymal, rna-seq
- GSE272957 EWSR1/FLI1 Expression in Human Mesenchymal Stem Cells derived from Experimental Teratomas Leads to Ewing´s Sarcoma Tumorigenesis [RNA-seq] 16 samples shares mesenchymal, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.