Altered Metabolomics and Inflammatory Transcriptomics in Human Bone Marrow Adipocytes After Acute High Calorie Diet and Acute Fasting
RNA-seq (gene expression) · human · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Altered metabolomics and inflammatory transcriptomics in human bone marrow adipocytes after acute high calorie diet and acute fastingFrontiers in endocrinology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297963_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1266176 and SRA study SRP587086. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 6 replicated groups read from 24 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9003188 High Calorie_Post_L6
- GSM9003189 High Calorie_Post_M2 High Calorie_Post_M
- GSM9003190 High Calorie_Post_M6 High Calorie_Post_M
- GSM9003191 High Calorie_Post_M8 High Calorie_Post_M
- GSM9003192 High Calorie_Post_N6 High Calorie_Post_N
- GSM9003193 High Calorie_Post_N10 High Calorie_Post_N
- GSM9003194 High Calorie_Pre_L5
- GSM9003195 High Calorie_Pre_M1 High Calorie_Pre_M
- GSM9003196 High Calorie_Pre_M5 High Calorie_Pre_M
- GSM9003197 High Calorie_Pre_M7 High Calorie_Pre_M
- GSM9003198 High Calorie_Pre_N5 High Calorie_Pre_N
- GSM9003199 High Calorie_Pre_N9 High Calorie_Pre_N
- GSM9003200 Fasting_Post_O8
- GSM9003201 Fasting_Post_L2 Fasting_Post_L
- GSM9003202 Fasting_Post_L4A
- GSM9003203 Fasting_Post_L8 Fasting_Post_L
- GSM9003204 Fasting_Post_M4
- GSM9003205 Fasting_Post_N2
- GSM9003206 Fasting_Pre_O7
- GSM9003207 Fasting_Pre_L1 Fasting_Pre_L
- GSM9003208 Fasting_Pre_L3A
- GSM9003209 Fasting_Pre_L7 Fasting_Pre_L
- GSM9003210 Fasting_Pre_M3A
- GSM9003211 Fasting_Pre_N1
- GSE283315 Investigation of the Altered Transcriptomic Dynamics of Bone Marrow Adipose Tissue Under Exogenous Stimuli in the Context of AML Pathogenesis 36 samples shares altered, marrow, bone
- GSE277476 Altered bone marrow myelopoiesis contributes to kidney injury [scRNA-seq] 11 samples shares altered, marrow, bone
- GSE312982 Human bone marrow adipocytes drive prostate cancer bone metastasis progression via lipid-mediated induction of Angiopoietin-like 4 10 samples shares adipocytes, marrow, bone
- GSE277474 Altered bone marrow myelopoiesis contributes to kidney injury [RNA-seq] 6 samples shares altered, marrow, bone
- GSE244379 Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13) 58 samples shares altered, acute
- GSE244446 Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13) [ACT-Seq] 32 samples shares altered, acute
- GSE244275 Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13) [4C-Seq] 10 samples shares altered, acute
- GSE273967 Loss of CD4 T cell responses to prior vaccines associate with inflammation and altered transcriptional signatures in HIV infection 174 samples shares altered
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.