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CMPortal: a community-oriented, data-driven resource to inform protocol design for cardiac modelling from human pluripotent stem cells

GSE298573 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/05/30 Platform GPL18573
Summary
Protocol design and benchmarking is central to optimise model development using human pluripotent stem cell derived cardiomyocytes (hPSC-CMs). By applying data mining to decades of research and hundreds of peer reviewed studies, we evaluate how protocol variables associate with common properties of cardiac functional and physiological maturation. This resource is publicly accessible through CMPortal, a community-oriented website providing custom navigation of the database, enabling researchers to benchmark protocol designs and outcomes for their dedicated applications. It hosts data-driven tools for researchers to leverage decades of knowledge gain across hundreds of hPSC-CM studies to inform strategies for studies in developmental biology, disease modelling, and drug screening.
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Direct links to NCBI, no account and no request form: the whole study as GSE298573_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1269955 and SRA study SRP588853. Searching any of these in the dataset finder brings you back here.

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