Pulsatile stretch stimulates endothelial PDGFB secretion to maintain arterial vascular smooth muscle
RNA-seq (gene expression) · human · 33 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 33 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Pulsatile flow dynamics determine pulmonary arterial architecturebioRxiv : the preprint server for biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE298790_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1271112 and SRA study SRP589333. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 33 more — browse all 33 samples with per-sample file links →
- GSE294621 Vascular-type heterogeneity is associated with differential gene expression profiles of endothelial cells under shear stress 74 samples shares endothelial, vascular
- GSE303084 Pressure Points: Endothelial Responses to Hemodynamic Stress in Health and Pulmonary Arterial Hypertension 72 samples shares endothelial, arterial
- GSE281329 Time-course Transcriptomics Reveals Impact of Treponema pallidum on Microvascular Endothelial Cell Function and Phenotype 39 samples shares endothelial, vascular
- GSE310554 Paired Vascular-Parenchymal Single Nuclei Sequencing Reveals Perturbed Endothelial-to-Mesenchymal Transition in Alzheimer’s Disease 39 samples shares endothelial, vascular
- GSE267498 Generation of hiPSC-derived brain microvascular endothelial cells using a combination of directed differentiation and transcriptional reprogramming strategies 37 samples shares endothelial, vascular
- GSE328189 Multiomic profiling of vascular endothelial cell differentiation from human embryonic stem cells [EC diff RNA-Seq] 36 samples shares endothelial, vascular
- GSE314942 Effect of hypoxanthine and pyroglutamic acid on downstream signaling mechanisms in vascular smooth muscle cells and endothelial cells. 36 samples shares endothelial, vascular
- GSE267418 Cytokine-induced memory-like responses in endothelial cells link chronic inflammation to vascular disease risk 35 samples shares endothelial, vascular
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.