Downregulation of Engulfment and cell motility 1 (Elmo1) induces quiescence and resistance to poly(I:C)-induced apoptosis in endothelial cells
RNA-seq (gene expression) · human · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 9 × C) 0 h vs 9 × C) 24 hGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Downregulation of Engulfment and cell motility 1 (Elmo1) induces quiescence and resistance to poly(I:C)-induced apoptosis in endothelial cellsCell death & disease · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE299038_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1272352 and SRA study SRP590067. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 2 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9031187 EA.hy926 cells, Mock, poly(I:C) 0 h_rep1 C) 0 h
- GSM9031188 EA.hy926 cells, Mock, poly(I:C) 0 h_rep2 C) 0 h
- GSM9031189 EA.hy926 cells, Mock, poly(I:C) 0 h_rep3 C) 0 h
- GSM9031190 EA.hy926 cells, siNT, poly(I:C) 0 h_rep1 C) 0 h
- GSM9031191 EA.hy926 cells, siNT, poly(I:C) 0 h_rep2 C) 0 h
- GSM9031192 EA.hy926 cells, siNT, poly(I:C) 0 h_rep3 C) 0 h
- GSM9031193 EA.hy926 cells, siELMO1, poly(I:C) 0 h_rep1 C) 0 h
- GSM9031194 EA.hy926 cells, siELMO1, poly(I:C) 0 h_rep2 C) 0 h
- GSM9031195 EA.hy926 cells, siELMO1, poly(I:C) 0 h_rep3 C) 0 h
- GSM9031196 EA.hy926 cells, Mock, poly(I:C) 24 h_rep1 C) 24 h
- GSM9031197 EA.hy926 cells, Mock, poly(I:C) 24 h_rep2 C) 24 h
- GSM9031198 EA.hy926 cells, Mock, poly(I:C) 24 h_rep3 C) 24 h
- GSM9031199 EA.hy926 cells, siNT, poly(I:C) 24 h_rep1 C) 24 h
- GSM9031200 EA.hy926 cells, siNT, poly(I:C) 24 h_rep2 C) 24 h
- GSM9031201 EA.hy926 cells, siNT, poly(I:C) 24 h_rep3 C) 24 h
- GSM9031202 EA.hy926 cells, siELMO1, poly(I:C) 24 h_rep1 C) 24 h
- GSM9031203 EA.hy926 cells, siELMO1, poly(I:C) 24 h_rep2 C) 24 h
- GSM9031204 EA.hy926 cells, siELMO1, poly(I:C) 24 h_rep3 C) 24 h
- GSE318549 NAD-dependent redox control enables endothelial quiescence and vascular stabilization during angiogenesis 15 samples shares endothelial, quiescence
- GSE178402 LncRNA HIF1A-AS1 regulates the apoptosis and proliferation of vascular endothelial cells through globally regulating miRNAs expression 24 samples shares endothelial, apoptosis
- GSE275647 Role of Cancer-Associated Fibroblasts in Prognostic Stratification of Advanced-Stage Gastric Cancer through Interacting with Endothelial and Malignant Epithelial Cells [AGC RNA-seq] 216 samples shares endothelial
- GSE286040 Endothelial Sensitivity to Pro-Fibrotic Signals Links Systemic exposure to Pulmonary Fibrosis 96 samples shares endothelial
- GSE254249 Remodeling of T and endothelial cells during total neoadjuvant therapy in rectal cancer 92 samples shares endothelial
- GSE294621 Vascular-type heterogeneity is associated with differential gene expression profiles of endothelial cells under shear stress 74 samples shares endothelial
- GSE303084 Pressure Points: Endothelial Responses to Hemodynamic Stress in Health and Pulmonary Arterial Hypertension 72 samples shares endothelial
- GSE327840 RNA-seq profiling of LPS tolerance in monocytes, THP-1, fibroblasts, smooth muscle cells, and endothelial cells 58 samples shares endothelial
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.