GEO series
E7386 enhances lenvatinib’s antitumor activity in preclinical models and human hepatocellular carcinoma.
GSE299215
Mus musculus; Homo sapiens
Expression profiling by high throughput sequencing
44 samples
2025/08/21
GPL30173GPL30172
Summary
To study the antitumor and antiangiogenic activity of combining E7386 (an oral protein-protein interaction inhibitor targeting CREB-binding protein (CBP)/β-catenin) with lenvatinib and explore a novel mechanism of action of E7386 that boosts antitumor response.
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Paper (PMID 40986544) ↗
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