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Transcriptomic profile of polarized WT or Mek1/2_tKO CD4+ T cells

GSE299327 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2026/05/05 Platform GPL24247
Summary
MEK1/2 are required for proper Tfh cell differentiation. To more specifically define the function of MEK1/2 signaling in Tfh cell development, we performed RNA-seq analysis.
Published in
The MEK1/2-IRF4 axis fosters T follicular helper cell differentiationand antitumor humoral immune response
Ran S, Wang S, Li R et al. · Journal of translational medicine 2026 · PMID 41840714 · doi:10.1186/s12967-026-08023-2
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Also filed as BioProject PRJNA1273919 and SRA study SRP590939. Searching any of these in the dataset finder brings you back here.

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