← BioTransfer GEO Dataset Finder
GEO series

The Ly6Ghigh neutrophil subset occupying the early metastatic niche dictates breast cancer lung metastasis via cathelicidin-induced CD8+ T cell death_neutrophil

GSE300115 Mus musculus Expression profiling by high throughput sequencing 9 samples Submitted 2026/03/12 Platform GPL28330
Summary
Lung metastasis is a leading cause of breast cancer (BC)-related mortality, driven by the immunosuppressive traits of the metastatic tumor microenvironment. However, the mechanisms underlying cell-cell crosstalk in shaping immune evasion within the metastatic niche remain poorly defined. Here, we try to decipher the interaction between the lymphocyte antigen 6 complex locus G6Dhigh (Ly6Ghigh) neutrophil subset and cluster of differentiation 8+ T lymphocytes (CD8+ T cells), and their role in promoting pulmonary metastasis of BC.
Published in
The Ly6g(high) Neutrophil Subset Dictates Breast Cancer Lung Metastasis via CD8(+) T Cell Death
Wang R, Liu X, Hou Y et al. · Cancer communications (London, England) 2026 · PMID 41625479 · doi:10.34133/cancomm.0003
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE300115_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1279054 and SRA study SRP592864. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 9 more — browse all 9 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.