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The gene expression profile of methotrexate-resistant JAR cells

GSE300458 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/02/21 Platform GPL24676
Summary
Choriocarcinoma is a rare and aggressive malignancy. Although multi-agent chemotherapy is the standard treatment, resistance to anticancer agents remains a significant clinical challenge. In this study, we investigated the gene expression profile of choriocarcinoma cells with acquired resistance to methotrexate (MTX) using mRNA sequencing.
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Direct links to NCBI, no account and no request form: the whole study as GSE300458_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1280993 and SRA study SRP594086. Searching any of these in the dataset finder brings you back here.

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