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ZDHHC13 Modulates Tumor Microenvironment Interactions to Suppress Melanoma Metastasis [RNA-Seq]

GSE302431 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/09/23 Platform GPL24247
Summary
This dataset supports a study investigating the role of ZDHHC13 in melanoma development. Using bulk RNA sequencing and 10x Genomics single-cell RNA sequencing, we analyzed how ZDHHC13 influences tumor progression and the tumor microenvironment. These data provide insights into the transcriptomic changes associated with ZDHHC13 activity in melanoma and serve as a resource for understanding gene expression dynamics in both tumor cells and surrounding immune components.
Published in
S-acyl transferase ZDHHC13 modulates tumor microenvironment interactions to suppress metastasis in melanoma models
Li H, Lyu J, Sun Y et al. · The Journal of clinical investigation 2025 · PMID 41321310 · doi:10.1172/JCI188249
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Direct links to NCBI, no account and no request form: the whole study as GSE302431_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1290927 and SRA study SRP600759. Searching any of these in the dataset finder brings you back here.

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