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The transcriptomic data of TCN1 overexpression in HaCaT cells

GSE302664 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2025/11/27 Platform GPL34284
Summary
This study aimed to explore the underlying molecular mechanism of TCN1 in driving psoriasis progression. TCN1 has been identified as an autoantigen and an endogenous activator of the IL-17 signaling pathway.
Published in
Transcobalamin 1 is a keratinocyte-derived autoantigen driving psoriasis through T helper 17 cell activation
Wang J, Li D, Zhai L et al. · Science advances 2026 · PMID 42030399 · doi:10.1126/sciadv.adv6716
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Also filed as BioProject PRJNA1291693 and SRA study SRP601055. Searching any of these in the dataset finder brings you back here.

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