GEO series
Transcriptome analysis of liver sinusoidal endothelial cells (LSECs) under palmitic acid treatment and IL-6/sIL-6R complex stimulation
GSE302884
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2026/04/01
GPL34284
Summary
This study investigates the transcriptional changes in liver sinusoidal endothelial cells (LSECs) following palmitic acid (PA) treatment and IL-6/sIL-6R complex stimulation. LSECs were cultured with PA for 12 hours and subsequently stimulated with the IL-6/sIL-6R complex for 1 hour to assess trans-signaling activation and gene expression changes. RNA sequencing was performed on four experimental groups: Control, PA, Complex, and PA+Complex.
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