GEO series
Human intranasal olfactory biopsy analysis of Alzheimer's Disease subjects
GSE302937
Homo sapiens
Expression profiling by high throughput sequencing
22 samples
2026/02/04
GPL34284
Summary
Single-cell RNA sequencing was performed on brush biopsy samples from the human olfactory epithelium (n = 22 donors) spanning control (n = 6), pre-clinical (n = 9) and clinical (n = 7) Alzheimer’s disease stages. The dataset comprises ~200,000 high-quality live cells encompassing neuronal, epithelial and immune lineages. These profiles enable comparative analyses of early neuroimmune changes associated with Alzheimer’s progression and provide a resource for identifying peripheral biomarkers of disease.
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Paper (PMID 41292796) ↗
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