Neoadjuvant Immune Checkpoint Blockade Before Chemoradiation for Patients with FIGO Stage IB3–IVA Cervical Squamous Carcinoma: GINECO Window-Of-Opportunity COLIBRI Study
RNA-seq (gene expression) · human · 96 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Cervical cancerThis series is part of our curated briefing on it.
- Samples
- 96 samples: 96 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trialNature communications · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE303300_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1294793 and SRA study SRP602724. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 96 sample titles: 96 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9122978 Targeted gene expression of patient ID021 at BEFRCT
- GSM9122979 Targeted gene expression of patient ID022 at BL
- GSM9122980 Targeted gene expression of patient ID022 at BEFRCT
- GSM9122981 Targeted gene expression of patient ID022 at 4WRCT
- GSM9122982 Targeted gene expression of patient ID023 at BEFRCT
- GSM9122983 Targeted gene expression of patient ID024 at BL
- GSM9122984 Targeted gene expression of patient ID024 at BEFRCT
- GSM9122985 Targeted gene expression of patient ID024 at 4WRCT
- GSM9122986 Targeted gene expression of patient ID025 at BL
- GSM9122987 Targeted gene expression of patient ID025 at BEFRCT
- GSM9122988 Targeted gene expression of patient ID026 at BL
- GSM9122989 Targeted gene expression of patient ID026 at BEFRCT
- GSM9122990 Targeted gene expression of patient ID026 at 4WRCT
- GSM9122991 Targeted gene expression of patient ID028 at BL
- GSM9122992 Targeted gene expression of patient ID028 at BEFRCT
- GSM9122993 Targeted gene expression of patient ID027 at 4WRCT
- GSM9122994 Targeted gene expression of patient ID027 at BL
- GSM9122995 Targeted gene expression of patient ID027 at BEFRCT
- GSM9122996 Targeted gene expression of patient ID028 at 4WRCT
- GSM9122997 Targeted gene expression of patient ID029 at BL
- GSM9122998 Targeted gene expression of patient ID029 at BEFRCT
- GSM9122999 Targeted gene expression of patient ID029 at 4WRCT
- GSM9123000 Targeted gene expression of patient ID030 at BL
- GSM9123001 Targeted gene expression of patient ID030 at BEFRCT
- GSM9123002 Targeted gene expression of patient ID030 at 4WRCT
- GSM9123003 Targeted gene expression of patient ID031 at BL
- GSM9123004 Targeted gene expression of patient ID031 at BEFRCT
- GSM9123005 Targeted gene expression of patient ID031 at 4WRCT
- GSM9123006 Targeted gene expression of patient ID032 at BL
- GSM9123007 Targeted gene expression of patient ID032 at BEFRCT
- GSM9123008 Targeted gene expression of patient ID032 at 4WRCT
- GSM9123009 Targeted gene expression of patient ID033 at BL
- GSM9123010 Targeted gene expression of patient ID033 at BEFRCT
- GSM9123011 Targeted gene expression of patient ID033 at 4WRCT
- GSM9123012 Targeted gene expression of patient ID034 at BL
- GSM9123013 Targeted gene expression of patient ID034 at BEFRCT
- GSM9123014 Targeted gene expression of patient ID036 at BL
- GSM9123015 Targeted gene expression of patient ID036 at BEFRCT
- GSM9123016 Targeted gene expression of patient ID036 at 4WRCT
- GSM9123017 Targeted gene expression of patient ID037 at BL
+ 56 more — browse all 96 samples with per-sample file links →
- GSE264492 Transcriptomic analysis reveals Streptococcus agalactiae activation of oncogenic pathways in cervical adenocarcinoma 24 samples same disease briefing · shares iva
- GSE291247 DLEU2 promotes cell motility and immune infiltration in cervical squamous cell carcinoma through reciprocal feed-forward activation of E2F1 16 samples same disease briefing · shares iva
- GSE305789 Activation of OSM-STAT3 Epigenetically Regulates Tumor-Promoting Transcriptional Programs in Cervical Cancer [RNA-Seq] 8 samples same disease briefing · shares iva
- GSE317187 A novel pyrrolidine-chalcone derivative exhibits synergistic anti-cervical cancer activity by dual-targeting MDM2-p53 axis and ferroptosis pathway 6 samples same disease briefing · shares iva
- GSE297038 Chemoradiation Reprograms Tumor Cells and Immune Microenvironment In Cervical Cancer [bulk RNA-seq] 34 samples same disease briefing · shares chemoradiation
- GSE316098 Spatial Transcriptomic Landscape of Invasion Patterns in Human Papillomavirus-Associated Endocervical Adenocarcinoma 186 samples same disease briefing
- GSE168244 Patient-derived organoids as a platform to study cervical cancer and viral infection 36 samples same disease briefing
- GSE299125 Paracrine Signals from HIV-1 Infected Immune Cells Reprogram Cervical Cancer Pathways 35 samples same disease briefing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.