GEO series

Methylation analysis of 81 glioma clinical samples (49 CIMP+ and 32 CIMP-) and 53 cell line samples

GSE30338 Homo sapiens Methylation profiling by genome tiling array 134 samples Submitted 2012/02/16 Platform GPL13534

Summary

Glioma CIMP (G-CIMP) is a powerful determinant of tumor pathogenicity but the molecular cause of G-CIMP is a fundamental question that is unresolved. Here, we show that mutation of a single gene, isocitrate dehydrogenase 1 (IDH1), directly causes the G-CIMP in gliomas by remodeling the methylome.

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Direct links to NCBI, no account and no request form: the whole study as GSE30338_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 134 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA154817. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 22343889) ↗

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