Super-enhancer-driven core transcription factor FOXP1 delays endothelial cell senescence via phase separation-mediated SESN3 activation_cuttag seq
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × P5 vs 3 × P15 vs 3 × P22 vs 3 × P30Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Super-enhancer-driven core transcription factor FOXP1 delays endothelial cell senescence via phase separation-mediated SESN3 activationTheranostics · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE303850_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1297755 and SRA study SRP604078. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9136901 P5-rep1 P5
- GSM9136902 P5-rep2 P5
- GSM9136903 P5-rep3 P5
- GSM9136904 P15-rep1 P15
- GSM9136905 P15-rep2 P15
- GSM9136906 P15-rep3 P15
- GSM9136907 P22-rep1 P22
- GSM9136908 P22-rep2 P22
- GSM9136909 P22-rep3 P22
- GSM9136910 P30_rep1 P30
- GSM9136911 P30_rep2 P30
- GSM9136912 P30_rep3 P30
- GSE303848 Super-enhancer-driven core transcription factor FOXP1 delays endothelial cell senescence via phase separation-mediated SESN3 activation_atac seq 8 samples shares foxp1, sesn3, super-enhancer-driven, separation-mediated, transcription, endothelial, senescence, activation
- GSE293855 Alphavirus M1 disrupts super-enhancer-driven oncogenic transcription in osteosarcoma [ChIP-seq] 8 samples shares super-enhancer-driven, transcription
- GSE293856 Alphavirus M1 disrupts super-enhancer-driven oncogenic transcription in osteosarcoma [RNA-seq] 32 samples shares super-enhancer-driven, transcription
- GSE291455 Super-enhancer-driven lncRNA HCG20 regulates pulmonary endothelial cell dysfunction through U2AF2-mediated pre-mRNA alternative splicing 4 samples shares super-enhancer-driven, endothelial
- GSE255690 Spatiotemporal transcriptomic changes of human ovarian aging and the key regulatory role of FOXP1 24 samples shares foxp1
- GSE268628 A novel ATG4B-SESN3 axis promotes the growth of T-cell acute lymphoblastic leukemia cells 6 samples shares sesn3
- GSE267758 Roles of super-enhancer-driven genes in T-ALL cells 16 samples shares super-enhancer-driven
- GSE303304 Super-enhancer-driven TCF4 promotes neuroblastoma metastasis by mediating GM3 synthesis [CUT&Tag] 3 samples shares super-enhancer-driven
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.