GEO series
CTCF (CCCTC-binding factor) binding patterns in the human genome following exposures to Clostridioides difficile TcdB.
GSE304121
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
10 samples
2026/02/11
GPL30173
Summary
This experiment uses a CUT&RUN approach to determine if the CCCTC-binding factor (CTCF) is altered in its ability to bind the human genome following exposure to TcdB. TcdB is a bacterial toxin and primary virulence factor produced by the enteric pathogen C. difficile. CTCF is a DNA binding protein that regulates gene transcription in the host.
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Paper (PMID 41513094) ↗
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