GEO series
Mirdametinib treatment for the osteofibrous dysplasia RASopathy
GSE305253
Homo sapiens
Expression profiling by high throughput sequencing
24 samples
2026/02/11
GPL30173
Summary
The goal of this study was to investigate the molecular response of primary cells cultured from the pseudarthrosis sites of Osteofibrous Dysplasia patients following 24h treatment with vehicle (DMSO), capmatinib (10uM, Catalog# S2788, Selleck Chemicals, USA), selumetinib (5uM, Catalog# S1008, Selleck Chemicals, USA), or mirdametinib (100nM, Catalog# S1036, Selleck Chemicals, USA). Transcriptional changes were
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Paper (PMID 41746735) ↗
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