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Osteocyte-specific deletion of Gasdermin D drives osteoarthritis cartilage degeneration by promoting inflammation and remodeling in subchondral bone

GSE305276 Mus musculus Expression profiling by high throughput sequencing 9 samples 2026/06/15 GPL24247
Summary
In osteoarthritis, we discovered that the number of osteocytes in the subchondral bone is reduced. By investigating the interaction between chondrocytes and osteocytes, we aim to elucidate the underlying pathological mechanisms.
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