Establishment and Characterization of a New Immortalized Human Oral Keratinocyte (HOK) Cell Line Harboring Various TP53 Mutations
RNA-seq (gene expression) · human · 15 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 15 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Establishment and characterization of a new immortalized human oral keratinocyte (HOK) cell line harboring various TP53 mutationsOral oncology · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE305620_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1307293 and SRA study SRP609578. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 15 more — browse all 15 samples with per-sample file links →
- GSE304320 Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network 36 samples shares tp53, mutations
- GSE304317 Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network [2] 24 samples shares tp53, mutations
- GSE252264 RIPK4 driven by TP53 mutations promotes resistance to PANoptosis and metastasis of CRC by phosphorylation of MTHFD1 18 samples shares tp53, mutations
- GSE297670 Splice-altering TP53 missense mutations: Drivers of functional loss and therapeutic targets via RNA modulation 18 samples shares tp53, mutations
- GSE252262 RIPK4 driven by TP53 mutations promotes resistance to PANoptosis and metastasis of CRC by phosphorylation of MTHFD1 [Anokis_seq] 12 samples shares tp53, mutations
- GSE280707 Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network [1] 12 samples shares tp53, mutations
- GSE34258 Genome sequencing of childhood medulloblastoma brain tumors links chromothripsis with TP53 mutations 49 samples shares tp53, mutations
- GSE228865 Effect of PHGDH knockdown on gene expression in human immortalized keratinocytes (HaCaT cells) 12 samples shares immortalized, keratinocyte
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.