TCR signaling via NFATc1 constrains IL-15-induced NK-like activation of human memory CD8+ T cells [RNAseq_IONO_12H]
RNA-seq (gene expression) · human · 40 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 40 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE305712_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1307501 and SRA study SRP609645. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 40 more — browse all 40 samples with per-sample file links →
- GSE306620 TCR signaling via NFATc1 constrains IL-15-induced NK-like activation of human memory CD8+ T cells 26 samples shares nfatc1, tcr, cd8, il-15-induced, constrains, activation
- GSE285617 Characterization and effective expansion of CD4-CD8- TCRab+ T cells from individuals living with type 1 diabetes 24 samples shares tcr, cd8
- GSE302214 scRNAseq and TCRseq of tumor infiltrating CD8 T cells from samples 22 samples shares tcr, cd8
- GSE299807 Similar activation-driven transcriptional programs in lung CMV- and flu- specific memory CD8+ T cells despite differences in tissue residency profiles 25 samples shares cd8, activation
- GSE312389 Delineating the role of co-stimulatory signals on human virus-specific memory CD8+ T cell activation and expansion using highly selective T cell receptor-targeted biologics 20 samples shares cd8, activation
- GSE235244 Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma suppress CD8+ T cell activation and inhibit response to immune checkpoint therapy [hPDAC] 8 samples shares cd8, activation
- GSE279781 CD137 agonism enhances anti-PD1 induced activation of clonally expanded CD8+ T cells in a neoadjuvant pancreatic cancer clinical trial 30 samples shares cd8, activation
- GSE266486 B cell directed CAR-T cell therapy results in activation of CD8+ cytotoxic CAR-negative bystander T cells in both non-human primates and patients (human) 21 samples shares cd8, activation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.